Document Details

Document Type : Article In Journal 
Document Title :
TREATMENT OF TEMPOROMANDIBULAR DISORDERS WITH INTRAARTICULAR INJECTION OF SODIUM HYALURONATE [CLINICO-RADIOGRAPHIC-BIOCHEMICAL STUDY]
TREATMENT OF TEMPOROMANDIBULAR DISORDERS WITH INTRAARTICULAR INJECTION OF SODIUM HYALURONATE [CLINICO-RADIOGRAPHIC-BIOCHEMICAL STUDY]
 
Document Language : English 
Abstract : Temporomandibular dysfunction has been considered as an abnormal condition that affects a wide range of population. This study was designed to assess the efficacy of intra-articular injection of sodium hyaluronate on the clinical signs and symptoms of patients with TMD. Fifteen patients (4 men, 11 women) of mean age 29.9y without radiographic evidences of arthritic changes or disc displacement changes were included in this study, after performing TMJ tomography and MRI sagittal scan. The patients were randomly allocated into 2 groups of unequal number, to detect arachidonic acid metabolites and cytokines, respectively, in their synovial fluid. The preauricular area was disinfected and anesthetized, then synovial fluid was collected. Sodium hyaluronate 1 ml (10 mg) was injected, and its effects on total amounts of arachidonic acid metabolites and cytokines and on clinical symptoms were measured. Results showed that; injection of sodium hyaluronate caused significant reduction in the mean amounts of leukotriene C4, 6 ketoprostaglandin F 1  and prostaglandin F2  together with interleukin-I  and interleukin-6. Similarly, the means of pain score and noise were significantly reduced, while the degree of mouth opening was significantly increased. These findings suggest that; inflammation plays a role in the pathogenesis of TMD and that injection of an anti-inflammatory substance may be useful. 
ISSN : 0 
Journal Name : Cairo Dental Journal 
Volume : 16 
Issue Number : 5 
Publishing Year : 2000 AH
2000 AD 
Article Type : Article 
Added Date : Saturday, March 20, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سعاد منصورMansour, Soad ResearcherDoctorate 

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