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Document Type |
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Article In Journal |
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Document Title |
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A COMPARATIVE HISTOLOGIC ANALYSIS OF THE USE OF A RESORBABLE COLLAGEN MEMBRANE AND ENAMEL MATRIX DERIVATIVE IN THE MANAGEMENT OF DEHISCENCETYPE DEFECTS تقييم أشعة الليزر المنخفضة الطاقة في علاج انحسار النسيج الطرفي الموضعي للثة في الانسان باستخدام رقعة نسيجية حرة |
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Document Language |
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English |
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Abstract |
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Several studies have documented the clinical efficiency of guided tissue regeneration (GTR)
with resorbable collagen membranes and enamel matrix derivative (EMD) in periodontal regenerative
therapy. The objective of this controlled experimental study was to compare the healing
process of dehiscence type critical sized defects treated by EMD, or GTR. Eight mongrel dogs were
used. Buccal osseous dehiscences were surgically created on the roots of maxillary canines, bilaterally.
The defects were randomly assigned to one of the treatments: root conditioning and EMD
application, or GTR with bioabsorbable Biomend ExtendT" collagen membrane. During the follow
up period, all animals showed uneventful healing with no serious adverse reactions. The dogs were
sacrificed at I and 3 months post surgically, and the blocks were processed. Qualitative assessment
of tissue health and reaction, periodontal regeneration and integrity of implanted materials was carried
out. Both treatment modalities resulted in true periodontal regeneration in the form of new cementum,
periodontal ligament and alveolar bone formation in the created defects. lvloreover,EMD
treated sites revealedboth acellularand cellularcementumdeposition,whereasGTR therapyresulted
mainly in cellular cementum formation. Regarding the new alveolar bone formation, EMD
group revealed superior results. Concerning tissue reaction, more inflammatory cells were observed
in GTR group, probably related to membrane disintegration. Within the limits of this study, it can be
concluded that EMD and Biomend ExtendT" membrane are almost equally effective in producing
true periodontal regeneration in periodontal dehiscence type defects, with EMD demonstrating
slightly better clinical healing and superior histologic results |
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ISSN |
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0 |
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Journal Name |
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Egyptian Dental Journal |
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Volume |
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52 |
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Issue Number |
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2 |
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Publishing Year |
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1426 AH
2006 AD |
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Article Type |
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Article |
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Added Date |
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Monday, October 18, 2010 |
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Researchers
| غادة منصور | Mansour, Ghada | Investigator | Doctorate | |
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