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Document Type |
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Article In Journal |
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Document Title |
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THE REGENERATIVE POTENTIAL OF PLATELET-RICH PLASMA: A.CLINICAL EV ALUA TION IN TREATMENT OF MANDIBULAR CLASS IIFURCATION DEFECTS IN CHRONIC PERIODONTITIS PATIENTS B.HISTOLOGICAL STUDY IN TREATMENT OF OSSEOUS DEFECTS IN DOGS القدرة التحديدية للاتين البلازما الغنية بالصفائح الدموية الذاتية أ- تقييم اكلينكي لمعالة العيوب الظيمة بين الجذور م الدرجة الثانية عند مرضى التهاب الانسجة حول السنية المزمن ب- دراسة هستولوجية لمعالجة العيوب العظيمة عند الكلاب |
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Document Language |
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English |
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Abstract |
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The purpose of this study was to evaluate
clinically and histologically the effectiveness
of PRP/Fisiograft@ and Fisiograft@ implant
material in the treatment of mandibular class II
furcation defects and surgically-induced
osseous defects in dogs . In 10 patients with
moderate to severe chronic periodontitis, 20
matched bilateral mandibular class II furcation
lesions constituted the study sample. All
patients received initial therapy, then when
qualified for surgery, defects were randomly
assigned as either receiving combination
therapy or Fisiograft@ alone. At baseline, 6
and 9 months postsurgically, clinical and
radiographic parameters evaluated included
probing depth (PD), vertical and horizontal
clinical attachment level (CAL-V and CAL-H
respectively),radiographic bone level(RBL),
and optical density (OD).Post surgical results
showed a significant improvement in all
studied variables at 6 and 9 months, when
compared to baseline in terms of pocket depth
reduction (PDR), gain in vertical and
horizontal attachment levels (AG-V, AG-H
respectively), improvement. in radiographic
bone level and optical density in both groups.
Significant differences were found only in combination group between 6 and 9 months
results in terms of PDR, AG-H and change in
00. Moreover, combination group revealed
statistically significant better results than
Fisiograft@ group for all variables throughout
the study period. To determine the nature of
periodontal healing, fourteen critical-sized
matched bilateral osseous defects were
surgically induced at the interproximal area of
mandibular 3rd and 4th premolars in 7 dogs.
Combination therapy was placed in seven
defects randomly assigned, whereas the
contralateral defects were implanted with
Fisiograft@ only. Six weeks later, the animals
were sacrificed and the mandibles were
processed for histologic evaluation. The
combination group demonstrated ample
evidence of periodontal regeneration in
comparison to Fisiograft@ group that showed
a less favourable regenerative outcome. |
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ISSN |
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0 |
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Journal Name |
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Alexandria Dental Journal |
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Volume |
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29 |
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Issue Number |
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4 |
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Publishing Year |
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1424 AH
2004 AD |
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Article Type |
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Article |
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Added Date |
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Tuesday, October 19, 2010 |
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Researchers
| غادة منصور | Mansour, Ghada | Investigator | Doctorate | |
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